Adding a certain compound to certain chemical reactions, such as: 58971-11-2, name is 3-Bromophenethylamine, belongs to bromides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 58971-11-2, Product Details of 58971-11-2
Di-tert-butyl dicarbonate (0.30 g, 1.38 mmol) and triethylamine (0.44 mL, 3.13 mmol) were added to a stirred solution of [2-(3-bromophenyl)ethyl]amine (0.25 g, 1.25 mmol) in tetrahydrofuran (2 mL) and the mixture was stirred at room temperature. After 3 hours ethyl acetate and water were added to the mixture. The organic layer was washed with brine, dried (Na2SO4) and evaporated. Purification of the residue by flash chromatography (8:2 hexanes/ethyl acetate) gave the title compound (0.29 g, 77%) as a solid.LRMS (m/z): 300/302 (M+1)+.1 H NMR (400 MHz, CHLOROFORM-d) delta ppm 1.44 (s, 9 H) 2.75-2.80 (m, 2 H) 3.36-3.41 (m, 2 H) 4.56 (br. s., 1 H) 7.10-7.20 (m, 2 H) 7.35 – 7.40 (m, 2 H)
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3-Bromophenethylamine, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Almirall, S.A.; Vidal Juan, Bernat; Forns Berenguel, Maria Pilar; Castillo Mcquade, Marcos; Erra Sola, Montserrat; Mir Cepeda, Marta; EP2441755; (2012); A1;,
Bromide – Wikipedia,
bromide – Wiktionary