Ormerod, W. E. published the artcileGranules and other changes in phase-contrast appearance produced by chemotherapeutic agents in trypanosomes, COA of Formula: C20H18BrN3, the publication is British Journal of Pharmacology and Chemotherapy (1963), 21(2), 259-72, database is CAplus and MEDLINE.
The morphological changes produced by 4 series of organic trypanocidal drugs were studied by quant. and by qual. methods using phase-contrast and fluorescence microscopy. Basic drugs (hydroxystilbamidine, quinapyramine, and homidium) were absorbed rapidly into the region of the kinetoplast; acidic drugs (suramin and related compounds) did not affect this region. Faint granules, which were present in some trypanosomes before the administration of drugs, absorbed the drugs and increased in contrast relative to the cytoplasm. Hydroxystilbamidine, quinapyramine, and related compounds, and possibly also suramin produced addnl. granules which did not contain drug. These addnl. granules are similar to the granules (volutin granules) which occur in trypanosome infections (not treated with drugs) when trypanosomes are about to be cleared from the blood. Homidium did not produce addnl. granules.
British Journal of Pharmacology and Chemotherapy published new progress about 518-67-2. 518-67-2 belongs to bromides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Benzene, name is Dimidium bromide, and the molecular formula is C20H18BrN3, COA of Formula: C20H18BrN3.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary