Trost, Barry M. published the artcileRuthenium-Catalyzed Cycloisomerizations of Diynols, Category: bromides-buliding-blocks, the publication is Journal of the American Chemical Society (2005), 127(13), 4763-4776, database is CAplus and MEDLINE.
A wide variety of diynols containing tertiary, secondary, and primary propargylic alcs. undergo a cycloisomerization reaction to form dienones and dienals in the presence of a catalytic amount of [CpRu(CH3CN)3]PF6. The formation of five- and six-membered rings is possible using this methodol. E.g., [CpRu(CH3CN)3]PF6 catalyzed the cycloisomerization of diynol I to give 45% dienal II. Secondary diynols react to form single geometrical isomeric dienones and dienals. Primary diynols undergo a cycloisomerization as well as a hydrative cyclization process. The utility of primary diynol cycloisomerization is demonstrated in a synthesis of (+)-α-kainic acid.
Journal of the American Chemical Society published new progress about 69361-41-7. 69361-41-7 belongs to bromides-buliding-blocks, auxiliary class PROTAC Linker,Aliphatic Linker, name is (4-Bromobut-1-yn-1-yl)trimethylsilane, and the molecular formula is C12H12F3N5O2, Category: bromides-buliding-blocks.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary