Lee, Yujin published the artcileAn Asymmetric Pathway to Dendrobine by a Transition-Metal-Catalyzed Cascade Process, Category: bromides-buliding-blocks, the publication is Angewandte Chemie, International Edition (2017), 56(40), 12250-12254, database is CAplus and MEDLINE.
An asym. pathway to the caged tetracyclic pyrrolidine alkaloid, dendrobine (I), is reported. The successful synthetic strategy features a one-pot, sequential palladium-catalyzed enyne cycloisomerization and rhodium-catalyzed diene-assisted pyrrolidine formation by allylic CH activation. The developed transition-metal-catalyzed cascade process permits rapid access to the dendrobine core structure II and circumvents the handling of labile intermediates. An intramol. aldol condensation under carefully defined reaction conditions takes place with a concomitant detosylation, followed by reductive amine methylation, to afford a late-stage intermediate (previously identified by several prior dendrobine syntheses) in only 10 synthetic steps overall.
Angewandte Chemie, International Edition published new progress about 69361-41-7. 69361-41-7 belongs to bromides-buliding-blocks, auxiliary class PROTAC Linker,Aliphatic Linker, name is (4-Bromobut-1-yn-1-yl)trimethylsilane, and the molecular formula is C7H13BrSi, Category: bromides-buliding-blocks.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary