Malamas, Michael S. published the artcileFacile synthesis of novel spiro[azetidine-2,4′(1’H)-isoquinoline-1′,3′,4(2’H)-triones], Application of (4-Bromo-2-fluorophenyl)methanamine hydrochloride, the publication is Journal of Heterocyclic Chemistry (1994), 31(2), 565-8, database is CAplus.
A convenient general method for the synthesis of a new heterocycle, spiro[azetidine-2,4′(1’H)-isoquinoline-1′,3′,4(2’H)-trione] (I, R1 = H, halo; R2 = Me, CH2C6H3FBr-2,4) is described. The key intermediate II (R = Cl) was prepared by direct halogenation of position-4 of acid II (R = H) with thionyl chloride, and subsequent treatment of the generated 4-Cl, 4-acetyl chloride derivative with a THF/NH3 solution at low temperature
Journal of Heterocyclic Chemistry published new progress about 147181-08-6. 147181-08-6 belongs to bromides-buliding-blocks, auxiliary class Fluoride,Bromide,Salt,Amine,Benzene, name is (4-Bromo-2-fluorophenyl)methanamine hydrochloride, and the molecular formula is C7H8BrClFN, Application of (4-Bromo-2-fluorophenyl)methanamine hydrochloride.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary