Luo, Yiyang published the artcileTotal Synthesis of trans-Resorcylide via Macrocyclic Stille Carbonylation, Application of (4-Bromobut-1-yn-1-yl)trimethylsilane, the publication is Journal of Antibiotics (2019), 72(6), 482-485, database is CAplus and MEDLINE.
The resorcylic macrolides are important natural products with a wide range of remarkable biol. activities. So far, most of the reported resorcylic macrolide syntheses use either macrolactonization or ring closing metathesis to build the corresponding macrocycle. In continuation of our efforts in developing novel carbonylation reactions to facilitate natural product total synthesis, we report herein a total synthesis of trans-resorcylide (I) featuring a palladium-catalyzed macrocyclic Stille carbonylation to build its 12-membered macrocycle.
Journal of Antibiotics published new progress about 69361-41-7. 69361-41-7 belongs to bromides-buliding-blocks, auxiliary class PROTAC Linker,Aliphatic Linker, name is (4-Bromobut-1-yn-1-yl)trimethylsilane, and the molecular formula is C7H13BrSi, Application of (4-Bromobut-1-yn-1-yl)trimethylsilane.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary