Doba, Takahiro published the artcileIron-catalysed regioselective thienyl C-H/C-H coupling, Computed Properties of 303734-52-3, the publication is Nature Catalysis (2021), 4(7), 631-638, database is CAplus.
Regioselective thienyl-thienyl coupling is arguably one of the most important transformations for organic electronic materials. A prototype of ideal organic synthesis to couple two thienyl groups by cutting two C-H bonds requires formal removal of two hydrogen atoms with an oxidant, which often limits the synthetic efficiency and versatility for oxidation-sensitive substrates (for example, donor and hole-transporting materials). Here, we found that di-Et oxalate, used together with AlMe3, acts as a two-electron acceptor in an iron-catalyzed C-H activation. We describe the regioselective thienyl C-H/C-H coupling with an iron(III) catalyst, a trisphosphine ligand, AlMe3 and di-Et oxalate under mild conditions. The efficient catalytic system accelerated by ligand optimization polymerizes thiophene-containing monomers into homo- and copolymers bearing a variety of electron-donative π motifs. The findings suggest the versatility of iron catalysis for the synthesis of functional polymers, for which the potential of this ubiquitous metal has so far not been fully appreciated.
Nature Catalysis published new progress about 303734-52-3. 303734-52-3 belongs to bromides-buliding-blocks, auxiliary class Thiophene,Bromide, name is 2-Bromo-3-(2-ethylhexyl)thiophene, and the molecular formula is C12H19BrS, Computed Properties of 303734-52-3.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary