Cory, Michael published the artcileInhibitors of histone methylation, SDS of cas: 518-67-2, the publication is Chemico-Biological Interactions (1974), 9(4), 253-9, database is CAplus and MEDLINE.
Two classes of inhibitors of histone methyltransferase I from calf thymus were studied. High concentrations (≥10mM) of various alkyl or aralkyl amines and polyamines were inhibitory to the enzyme. Spermine and spermidine were among the most potent compounds in this group. The best monoamine inhibitor was 2-phenylethylamine, which gave 47% inhibition at 10mM. The substituted phenanthridinium compound ethidium bromide was also an inhibitor of the enzyme. A number of analogs of ethidium bromide were tested, and the most potent compound gave 50% inhibition at 0.125mM. S-adenosyl-L-methionine showed competitive inhibition of the enzyme as determined from a Lineweaver-Burk plot, whereas ethidium bromide was noncompetitive.
Chemico-Biological Interactions published new progress about 518-67-2. 518-67-2 belongs to bromides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Benzene, name is Dimidium bromide, and the molecular formula is C20H18BrN3, SDS of cas: 518-67-2.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary