Lee, Mitchell T. published the artcileSynthesis of Isomerically Pure (Z)-Alkenes from Terminal Alkynes and Terminal Alkenes: Silver-Catalyzed Hydroalkylation of Alkynes, Application of 7-Bromohept-1-yne, the publication is Journal of the American Chemical Society (2019), 141(43), 17086-17091, database is CAplus and MEDLINE.
Here, an efficient synthesis of diastereopure Z-alkenes (Z:E > 300:1) through a silver-catalyzed hydroalkylation of terminal alkynes using alkylboranes as coupling partners is demonstrated. The exploration of the substrate scope, which reveals the broad functional group compatibility of the new method, is also described. Preliminary mechanistic studies suggest that a 1,2-metalate rearrangement of the silver borate intermediate is the key step responsible for the stereochem. outcome of the reaction.
Journal of the American Chemical Society published new progress about 81216-14-0. 81216-14-0 belongs to bromides-buliding-blocks, auxiliary class Linker,PROTAC Linker, name is 7-Bromohept-1-yne, and the molecular formula is C7H11Br, Application of 7-Bromohept-1-yne.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary