Simultaneous determination of salinomycin and monensin in chicken meat by HPLC was written by Miyakawa, Hiroyuki;Horii, Shozo;Kokubo, Yataro. And the article was included in Shokuhin Eiseigaku Zasshi in 1995.Name: 2-Bromo-1-(pyren-1-yl)ethanone The following contents are mentioned in the article:
A method for simultaneous determination of salinomycin and monensin in chicken meat by HPLC with a fluorescence detector was developed. Salinomycin and monensin were extracted with MeCN from a meat sample. The extract was partitioned between Et acetate and water, and the Et acetate layer was cleaned up with a Sep-pak Silica cartridge. Salinomycin and monensin were reacted with 1-bromoacetylpyrene to form fluorescent derivatives After clean-up with a Sep-pak Florisil cartridge, the derivatives were determined by HPLC with a fluorescence detector. The recoveries of salinomycin and monensin from chicken meat spiked at the levels of 0.1 ppm and 1 ppm were 66.2-96.2%. The detection limits were 0.05 ppm for the 2 antibiotics. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Name: 2-Bromo-1-(pyren-1-yl)ethanone).
2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Name: 2-Bromo-1-(pyren-1-yl)ethanone
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary