Page, Brent D. G. published the artcileInhibiting Aberrant Signal Transducer and Activator of Transcription Protein Activation with Tetrapodal, Small Molecule Src Homology 2 Domain Binders: Promising Agents against Multiple Myeloma, Quality Control of 21101-63-3, the publication is Journal of Medicinal Chemistry (2013), 56(18), 7190-7200, database is CAplus and MEDLINE.
[(Arylsulfonyl)glycinyl](cyclohexylbenzyl)aminosalicylic acids such as I (R = 4-MeC6H4, F5C6; R1 = 2-F3CC6H4) were prepared as inhibitors of the signal transducer and activator of transcription (STAT) protein Stat3 for potential use as treatments for multiple myeloma. The hydrophobicities of I and their inhibition of Stat3 were determined; mol. docking of selected compounds to the SH2 domain of Stat3 and inhibition of Stat3 phosphorylation under various conditions were determined for selected compounds, and the activity of I (R = 4-MeC6H4; R1 = 2-F3CC6H4) against human multiple myeloma cells and human hematopoietic cells and its induction of apoptosis in multiple myeloma cells was determined
Journal of Medicinal Chemistry published new progress about 21101-63-3. 21101-63-3 belongs to bromides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Bromide,sulfides,Benzyl bromide,Benzene, name is (4-(Bromomethyl)phenyl)(trifluoromethyl)sulfane, and the molecular formula is C8H6BrF3S, Quality Control of 21101-63-3.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary