Application of 15155-41-6, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 15155-41-6, name is 4,7-Dibromo-2,1,3-benzothiadiazole belongs to bromides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
4,7-Dibromo-2,1,3-benzothiadiazole (12.204 g, 42.5 mmol) was added to a 500 ml three-neck round bottom flask, dissolved in 400 ml of absolute ethanol, passed through a nitrogen atmosphere, and cooled to 0 C. NaBH4 (15.69 g, 425 mmol) was added portionwise to the solution. After the addition of NaBH4, the reaction mixture was transferred to room temperature overnight. The reaction solution was poured into a beaker, and the solid precipitated in the bottle was completely dissolved by adding 50 ml of water. The large amount of ethanol in the bottle was removed, extracted with dichloromethane and water, and the combined organic phases were washed with water, dried over anhydrous magnesium sulfate and filtered.The filtrate was distilled under reduced pressure to give a pale yellow solid (7.583 g, 28.74 mmol, 67.6%).That is, 3,6-dibromo-1,2-phenylenediamine, the structural formula is:
The synthetic route of 4,7-Dibromo-2,1,3-benzothiadiazole has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Jiangxi Normal University; Liang Aihui; Zhou Wenjing; Xie Qi; Zhang Jiayu; Liu Zhiqian; Hu Sifan; (26 pag.)CN110204561; (2019); A;,
Bromide – Wikipedia,
bromide – Wiktionary