Goodman, Allan J.’s team published research in Bioorganic & Medicinal Chemistry Letters in 19 | CAS: 111865-47-5

Bioorganic & Medicinal Chemistry Letters published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C10H16Br3N, Synthetic Route of 111865-47-5.

Goodman, Allan J. published the artcileCB2 selective sulfamoyl benzamides: Optimization of the amide functionality, Synthetic Route of 111865-47-5, the publication is Bioorganic & Medicinal Chemistry Letters (2009), 19(2), 309-313, database is CAplus and MEDLINE.

Previous research within our laboratories identified sulfamoyl benzamides as novel cannabinoid receptor ligands. Optimization of the amide linkage led to the reverse amide 40. The compound exhibited robust antiallodynic activity in a rodent pain model when administered i.p. Efficacy after oral administration was observed only when ABT, a cytochrome P 450 suicide inhibitor, was coadministered.

Bioorganic & Medicinal Chemistry Letters published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C10H16Br3N, Synthetic Route of 111865-47-5.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary