Shintani, Ryo published the artcileA new entry of nucleophiles in rhodium-catalyzed asymmetric 1,4-addition reactions: addition of organozinc reagents for the synthesis of 2-aryl-4-piperidones, Formula: C7H6BrF, the main research area is pyridinone arylzinc chloride conjugate addition; arylpiperidone asym preparation; rhodium conjugate addition catalyst.
A rhodium-catalyzed asym. 1,4-addition reaction has been applied to the synthesis of 2-aryl-4-piperidones, e.g., I. While other conventional nucleophiles failed, organozinc reagents have been successfully utilized for the construction of these useful compounds in very good yield and enantiomeric excess.
Journal of the American Chemical Society published new progress about Conjugate addition reaction, stereoselective. 452-63-1 belongs to class bromides-buliding-blocks, name is 1-Bromo-4-fluoro-2-methylbenzene, and the molecular formula is C7H6BrF, Formula: C7H6BrF.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary