《Tandem Condensation-Hydrogenation to Produce Alkylated Nitriles Using Bifunctional Catalysts: Platinum Nanoparticles Supported on MOF-Derived Carbon》 was written by Huang, Ao; Nie, Renfeng; Zhang, Biying; Pei, Yuchen; Chen, Minda; Behera, Ranjan; Yu, Jiaqi; Luan, Xuechen; Hunter, Nicholas T.; Ke, Ming; Huang, Wenyu. Product Details of 6630-33-7 And the article was included in ChemCatChem in 2020. The article conveys some information:
Tandem catalysis, which allows multiple steps of a reaction to take place without the need for separation and purification, is highly desired for the design of efficient and environmentally-friendly chem. processes. Herein, the pyrolysis of UiO-66-NH2, an amino-functionalized metal-organic framework, produces nitrogen-rich carbon-ZrO2 composite (CN-ZrO2). This composite is rich in basic sites and effectively catalyzes the Knoevenagel condensation reaction. After loading Pt nanoparticles onto this composite support, a tandem catalyst (Pt/CN-ZrO2) is produced to be capable of the one-step Knoevenagel condensation-hydrogenation reaction to produce an alpha-alkylated nitrile. The tandem catalyst exhibits >99% aldehyde conversion and >99% selectivity toward alpha-alkylated nitrile under 1 MPa H2 at 80°C. This catalyst could be reused for five times in the presence of malononitrile without significant deactivation and is versatile for one-step condensation-hydrogenation of various aldehydes. The good performance of Pt/CN-ZrO2 could be ascribed to the synergistic interaction between Pt and CN-ZrO2 composite supports that lead to the appropriate hydrogenation activity of supported Pt nanoparticles. The results came from multiple reactions, including the reaction of o-Bromobenzaldehyde(cas: 6630-33-7Product Details of 6630-33-7)
o-Bromobenzaldehyde(cas: 6630-33-7) is used in L-threonine aldolase-catalyzed enantio/diastereoselective aldol reactions.Product Details of 6630-33-7It is also used in L-threonine aldolase-catalyzed enantio and diastereoselective aldol reactions. Further, it reacts with trichloromethane to prepare 1-(2-bromo-phenyl)-2,2,2-trichloro-ethanol.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary