《Palladium-Catalyzed Three-Component Coupling Reaction of o-Bromobenzaldehyde, N-Tosylhydrazone, and Methanol》 was published in Organic Letters in 2020. These research results belong to Zhu, Lei; Ren, Xiaojian; Yu, Yinghua; Ou, Pengcheng; Wang, Zhi-Xiang; Huang, Xueliang. Application of 6630-33-7 The article mentions the following:
A ligand-controlled palladium-catalyzed three-component reaction of o-bromoaryl aldehydes, N-tosylhydrazones and methanol was described for the synthesis of aryl esters such as I [R = H, 3-OMe, 4-F, etc.; Ar = Ph, 3-MeC6H4, 2-thienyl, etc.]. This reaction used readily available compounds as starting materials while displaying a broad substrate scope and good functional group compatibility. This methodol. was also extended to the synthesis of [methoxy(aryl)methyl]benzaldehydes II [R1 = H, 4-Me, 5-Cl, etc.; R2 = H, Me, OMe, etc.]. After reading the article, we found that the author used o-Bromobenzaldehyde(cas: 6630-33-7Application of 6630-33-7)
o-Bromobenzaldehyde(cas: 6630-33-7) is used in L-threonine aldolase-catalyzed enantio/diastereoselective aldol reactions.Application of 6630-33-7It is a key starting material in the total synthesis of an anticancer agent, (-)-taxol.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary