《Metal-Free C-S Bond Formation in Elemental Sulfur and Cyclobutanol Derivatives: The Synthesis of Substituted Thiophenes》 was written by Wu, Mingzhong; Yan, Chaoxian; Zhuang, Daijiao; Yan, Rulong. Computed Properties of C7H5BrO2This research focused onthiophene preparation; cyclobutanol elemental sulfur bond formation. The article conveys some information:
A general approach for the metal-free synthesis of thiophenes by tert-cyclobutanols and elemental sulfur was developed. This protocol provided a strategy for constructing multisubstituted thiophene derivatives via C-S bond formation under air. This reaction showed good functionality tolerance under the reaction conditions, and the mechanism was validated by control experiments and d. functional theory calculations After reading the article, we found that the author used 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4Computed Properties of C7H5BrO2)
Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.Computed Properties of C7H5BrO2
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary