On April 30, 2020, Kim, Jong Seung; Sharma, Amit; Lee, Min Goo; Won, Miae; Lee, Jin Yong; Chi, Sung-Gil; Sessler, Jonathan L. published a patent.Quality Control of (6-Bromohexyl)triphenylphosphonium bromide The title of the patent was Anticancer prodrug for overcoming drug resistance. And the patent contained the following:
Disclosed is an anticancer prodrug that disturbs energy metabolism in cancer cells to overcome drug resistance. The anticancer prodrug has a structure including a pyruvate dehydrogenase kinase (PDK) inhibitor moiety, a mitochondrial targeting group, and an anthracycline moiety reversibly connected to the PDK inhibitor moiety and the targeting group. The experimental process involved the reaction of (6-Bromohexyl)triphenylphosphonium bromide(cas: 83152-22-1).Quality Control of (6-Bromohexyl)triphenylphosphonium bromide
The Article related to anticancer prodrug drug resistance pyruvate dehydrogenase kinase inhibitor, Pharmaceuticals: Pharmaceutics and other aspects.Quality Control of (6-Bromohexyl)triphenylphosphonium bromide
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary