On June 23, 2022, Long, Alan; Liu, Chun Yu; Liu, Chunliang; Zhou, Yasheen; Pulley, Shon R.; Graham, Keith Andrew Newton published a patent.Product Details of 1160653-94-0 The title of the patent was Boron containing pyrazole compounds, compositions comprising them, methods and uses thereof. And the patent contained the following:
The present invention describes novel boron containing pyrazole compounds, e.g. I, or their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their medical uses. The compounds of the invention have activity as Janus kinase (JAK) inhibitors and are useful in the treatment or control of inflammation, auto-immune diseases, cancer, and other disorders and indications where modulation of JAK would be desirable. Also described are methods of treating inflammation, auto-immune diseases, cancer, and other conditions that are susceptible to the inhibition of a Janus kinase by administering a compound herein described. The experimental process involved the reaction of 3-Bromo-2-fluoro-6-methoxybenzaldehyde(cas: 1160653-94-0).Product Details of 1160653-94-0
The Article related to boron amidopyrazole preparation janus kinase inhibition autoimmune anticancer, Organometallic and Organometalloidal Compounds: Boron Compounds and other aspects.Product Details of 1160653-94-0
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary