Borylation of Unactivated C(sp3)-H Bonds with Bromide as a Traceless Directing Group was written by Zhang, Ge;Li, Meng-Yao;Ye, Wen-Bo;He, Zhi-Tao;Feng, Chen-Guo;Lin, Guo-Qiang. And the article was included in Organic Letters in 2021.Electric Literature of C10H11BrO2 This article mentions the following:
A Pd-catalyzed alkyl C-H borylation of aryl bromides with bromide as a traceless directing group is described, providing a convenient approach to access alkyl boronates bearing a 閻?all-C quaternary stereocenter. The protocol features a broad substrate scope, excellent site selectivity, and good functional group tolerance. In the experiment, the researchers used many compounds, for example, Ethyl (2-bromophenyl)acetate (cas: 2178-24-7Electric Literature of C10H11BrO2).
Ethyl (2-bromophenyl)acetate (cas: 2178-24-7) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Electric Literature of C10H11BrO2
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary