Regio- and Chemoselective C-H Chlorination/Bromination of Electron-Deficient Arenes by Weak Coordination and Study of Relative Directing-Group Abilities was written by Sun, Xiuyun;Shan, Gang;Sun, Yonghui;Rao, Yu. And the article was included in Angewandte Chemie, International Edition in 2013.Name: Ethyl (2-bromophenyl)acetate This article mentions the following:
A palladium(II)-catalyzed ortho-chlorination/bromination reaction was developed using electron-deficient arenes as substrates. A preliminary evaluation was conducted on the relative abilities of the directing groups. In the experiment, the researchers used many compounds, for example, Ethyl (2-bromophenyl)acetate (cas: 2178-24-7Name: Ethyl (2-bromophenyl)acetate).
Ethyl (2-bromophenyl)acetate (cas: 2178-24-7) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon闂佺偨鍎茶ぐ绲﹐mine bond is electrophilic, i.e. alkyl bromides are alkylating agents. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Name: Ethyl (2-bromophenyl)acetate
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary