Song, Senchuan et al. published their research in Molecules in 2013 | CAS: 4457-67-4

1-Bromo-4-methoxybutane (cas: 4457-67-4) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Name: 1-Bromo-4-methoxybutane

Design, synthesis and evaluation of N13-substituted evodiamine derivatives against human cancer cell lines was written by Song, Senchuan;Chen, Zhiyong;Li, Shaoxue;Huang, Yanmin;Wan, Yiqian;Song, Huacan. And the article was included in Molecules in 2013.Name: 1-Bromo-4-methoxybutane This article mentions the following:

Attempting to improve the anticancer activity and solubility of evodiamine in simulated gastric fluid (SGF) and simulated intestinal fluid (SIF) solutions, thirty-eight N13-substituted evodiamine derivatives were designed, synthesized and tested for antitumor activity against six kinds of human cancer cell lines, namely prostate cancer (DU-145 and PC-3), lung cancer (H460), breast cancer (MCF-7), colon cancer (HCT-5) and glioblastoma (SF-268). The solubility of these compounds in SGF and SIF solutions was evaluated and apoptosis induced the title compounds was determined The results showed that among all compounds examined, several showed the highest antitumor activity and a broader spectrum of activity, with IC50 values ranging from 1-2 婵炴挾鎷? Their solubility was obviously improved and several compounds had a significant impact inducing apoptosis in some cancer cell lines. The preliminary structure-activity relationships of these derivatives were discussed. The synthesis of the target compounds was achieved by alkylation of (13bS)-8,13,13b,14-tetrahydro-14-(methyl)indolo[2′,3′:3,4]pyrido[2,1-b]quinazolin-5(7H)-one (evodiamine) with alkylation agents, such as alkyl bromides. In the experiment, the researchers used many compounds, for example, 1-Bromo-4-methoxybutane (cas: 4457-67-4Name: 1-Bromo-4-methoxybutane).

1-Bromo-4-methoxybutane (cas: 4457-67-4) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Name: 1-Bromo-4-methoxybutane

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary