Copper-catalyzed three-component reaction of arylhydrazine hydrochloride, DABSO, and NFSI for the synthesis of arenesulfonyl fluorides was written by Pan, Qijun;Liu, Yongan;Pang, Wan;Wu, Jingjing;Ma, Xiaoyu;Hu, Xiaojun;Guo, Yong;Chen, Qing-Yun;Liu, Chao. And the article was included in Organic & Biomolecular Chemistry in 2021.Name: 3-Bromobenzene-1-sulfonyl fluoride This article mentions the following:
This paper reports a convenient copper-catalyzed three-component conversion of arylhydrazine hydrochlorides RNHNH2.HCl (R = 4-bromophenyl, naphthalen-2-yl, quinolin-7-yl, etc.) to arenesulfonyl fluorides RS(O)2F in good yields under mild conditions, using 1,4-diazabicyclo [2.2.2]octane bis(sulfur dioxide) (DABSO) as a sulfonyl source and N-fluorobenzenesulfonimide (NFSI) as a fluorine source based on a radical sulfur dioxide insertion and fluorination strategy. Notably, arylhydrazine hydrochloride is used as a safe precursor of aryl radicals. In the experiment, the researchers used many compounds, for example, 3-Bromobenzene-1-sulfonyl fluoride (cas: 454-65-9Name: 3-Bromobenzene-1-sulfonyl fluoride).
3-Bromobenzene-1-sulfonyl fluoride (cas: 454-65-9) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon闁艰京鐗梤omine bond is electrophilic in nature. The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.Name: 3-Bromobenzene-1-sulfonyl fluoride
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary