Nambo, Masakazu et al. published their research in ACS Catalysis in 2022 | CAS: 18791-79-2

5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.HPLC of Formula: 18791-79-2

Desulfonylative Coupling of Alkylsulfones with gem-Difluoroalkenes by Visible-Light Photoredox Catalysis was written by Nambo, Masakazu;Ghosh, Koushik;Yim, Jacky C.-H.;Tahara, Yasuyo;Inai, Naoto;Yanai, Takeshi;Crudden, Cathleen M.. And the article was included in ACS Catalysis in 2022.HPLC of Formula: 18791-79-2 This article mentions the following:

The desulfonylative radical addition of tertiary alkyl groups I [R1 = 2-phenylethyl, 1,3-dioxolan-2-ylmethyl, prop-2-en-1-yl, etc. R2 = Me, 3-chloropropyl, 2-(tert-butoxy)-2-oxoethyl, etc.; R1 = R2 = -(CH2)5-, -(CH2)2O(CH2)2-, 2,3-dihydro-1H-inden-2-ylidene; R3 = H, Me] to gem-difluoroalkenes F2C=CHR4 (R4 = 4-(4-chlorophenyl)phenyl, naphthalen-2-yl, 1-benzothiophen-3-yl, etc.) by photoredox Ir-catalyst was described. This method exhibits broad substrate scope, affording structurally diverse (E)-fluoroalkene derivatives (R1)(R2)R3CC(F)=CHR4 in a highly stereoselective manner. The resulting (E)-fluoroalkenes were converted into complex fused cyclic compounds e.g., II by intramol. cyclization reactions. Control experiments and theor. calculations are consistent with a single Ir catalyst playing the dual role of generating radical species from sulfones via single electron transfer and mediating Z/E isomerization via energy transfer. A subset of fluoroalkenes provided Z stereoisomers with <90% selectivity, but the same alkenes could also be obtained as E isomers (R1)(R2)R3CC(F)=CHR4 (R1 = 2-phenylethyl, R2 = R3 = Me, R4 = m-OMe, m-Br, p-Me.) with high selectivity by taking advantage of a secondary Z to E photoisomerization. In the experiment, the researchers used many compounds, for example, 5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2HPLC of Formula: 18791-79-2).

5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.HPLC of Formula: 18791-79-2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary