Ethyl p-(2-methyl-3-oxopropyl)- and p-(2-methyl-3-oxo-1-propenyl)benzoates: preparation and use in the synthesis of biologically active derivatives of p-(nor-polyprenyl)benzoic acids was written by Kryshtal, G. V.;Zhdankina, G. M.;Serebryakov, E. P.. And the article was included in Izvestiya Akademii Nauk, Seriya Khimicheskaya in 1993.Application of 28322-40-9 This article mentions the following:
The title esters were prepared via saturated and unsaturated aldehyde ester intermediates, which are easily available from the Pd-catalyzed reaction of Et 4-bromobenzoate with methallyl alc. and the aldol condensation of Et 4-formylbenzoate with propanal. In vitro bioassays for some of the synthesized compounds are compared with earlier data on their pharmacol. effects in vivo. In the experiment, the researchers used many compounds, for example, Isopentyltriphenylphosphonium bromide (cas: 28322-40-9Application of 28322-40-9).
Isopentyltriphenylphosphonium bromide (cas: 28322-40-9) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Application of 28322-40-9
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary