One-Pot Copper-Catalyzed Three-Component Reaction of Sulfonyl Azides, Alkynes and Allylamines To Access 2,3-Dihydro-1H-imidazo[1,2-a]indoles was written by Jin, Hongwei;Liu, Daohong;Zhou, Bingwei;Liu, Yunkui. And the article was included in Synthesis in 2020.Reference of 85118-24-7 This article mentions the following:
A copper-catalyzed multicomponent reaction of sulfonyl azides, alkynes and allylamines affording 2,3-dihydro-1H-imidazo-[1,2-a]indoles in moderate yields was reported. Four C-N bonds were constructed by way of azide-alkyne cycloaddition (CuAAC) and double Ullmann-type coupling reactions in a one-pot process. In the experiment, the researchers used many compounds, for example, 2-Bromo-4-(trifluoromethyl)benzaldehyde (cas: 85118-24-7Reference of 85118-24-7).
2-Bromo-4-(trifluoromethyl)benzaldehyde (cas: 85118-24-7) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.Reference of 85118-24-7
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary