3-Halogeno-2-, 4- and 6-aminophenol was written by Hodgson, Herbert H.;Kershaw, Arnold. And the article was included in Journal of the Chemical Society in 1928.Application In Synthesis of 4-Amino-3-bromophenol This article mentions the following:
3-Chloro-2-aminophenol, m. 122鎺? by reduction of the corresponding NO2 derivative (HCl salt, plates); 3-Br derivative, m. 138鎺?(HCl salt, needles); 3-I derivative, m. 137鎺?(decomposition) (HCl salt, plates). 3-Chloro-4-aminophenol, m. 159.5鎺?(HCl salt, plates); 3-Br derivative, m. 151鎺?(HCl salt, prisms); 3-I derivative, m. 145.5鎺?(HCl salt, plates). 3-Chloro-6-aminophenol, m. 154鎺?(HCl salt, plates); 3-Br derivative, m. 150鎺?(HCl salt, plates); 3-I derivative, m. 141鎺?(HCl salt, plates). Color reactions of these compounds with FeCl3, bleaching powder solution and Br-H2O are given. In the experiment, the researchers used many compounds, for example, 4-Amino-3-bromophenol (cas: 74440-80-5Application In Synthesis of 4-Amino-3-bromophenol).
4-Amino-3-bromophenol (cas: 74440-80-5) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon閳ユ彽romine bond is electrophilic, i.e. alkyl bromides are alkylating agents. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Application In Synthesis of 4-Amino-3-bromophenol
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary