Hildebrand, Catherine et al. published their research in Journal of Medicinal Chemistry in 1990 | CAS: 615-55-4

3,4-Dibromoaniline (cas: 615-55-4) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Recommanded Product: 3,4-Dibromoaniline

Structure-activity relationships of N2-substituted guanines as inhibitors of HSV1 and HSV2 thymidine kinases was written by Hildebrand, Catherine;Sandoli, Daniele;Focher, Federico;Gambino, Joseph;Ciarrocchi, Giovanni;Spadari, Silvio;Wright, George. And the article was included in Journal of Medicinal Chemistry in 1990.Recommanded Product: 3,4-Dibromoaniline This article mentions the following:

Guanines I [R = Ph, substituted Ph, Bu, hexyl, (CH2)5OH, CH2Ph, CH2C6H4Cl] were prepared and tested for inhibition of the thymidine kinases encoded by Herpes simplex viruses type 1 and type 2. Compounds with hydrophobic, electron-attracting groups in the meta position of the Ph ring such as I (R = 3-CF3C6H4) were the most potent inhibitors of both enzymes. Many derivatives were significantly more potent against the type 2 thymidine kinase than against the type 1 and can effectively discriminate between the two enzymes. I [R = alkyl, (un)substituted CH2Ph] were moderately potent inhibitors, and the type 2 enzyme was again more sensitive than the type 1 enzyme. None of the compounds inhibited the thymidine kinase isolated from the host HeLa cell line, suggesting that members of this class of compounds may be useful nonsubstrate, antiviral compounds for latent herpesvirus infections. In the experiment, the researchers used many compounds, for example, 3,4-Dibromoaniline (cas: 615-55-4Recommanded Product: 3,4-Dibromoaniline).

3,4-Dibromoaniline (cas: 615-55-4) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Recommanded Product: 3,4-Dibromoaniline

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary