Analyzing Site Selectivity in Rh2(esp)2-Catalyzed Intermolecular C-H Amination Reactions was written by Bess, Elizabeth N.;DeLuca, Ryan J.;Tindall, Daniel J.;Oderinde, Martins S.;Roizen, Jennifer L.;Du Bois, J.;Sigman, Matthew S.. And the article was included in Journal of the American Chemical Society in 2014.Quality Control of Isopentyltriphenylphosphonium bromide This article mentions the following:
Predicting site selectivity in C-H bond oxidation reactions involving heteroatom transfer is challenged by the small energetic differences between disparate bond types and the subtle interplay of steric and electronic effects that influence reactivity. Herein, the factors governing selective Rh2(esp)2-catalyzed C-H amination of isoamylbenzene derivatives are investigated, where modification to both the nitrogen source, a sulfamate ester, and substrate are shown to impact isomeric product ratios. Linear regression math. modeling is used to define a relationship that equates both IR stretching parameters and Hammett 锜?sup>+ values to the differential free energy of benzylic vs. tertiary C-H amination. This model has informed the development of a novel sulfamate ester, which affords the highest benzylic-to-tertiary site selectivity (9.5:1) observed for this system. In the experiment, the researchers used many compounds, for example, Isopentyltriphenylphosphonium bromide (cas: 28322-40-9Quality Control of Isopentyltriphenylphosphonium bromide).
Isopentyltriphenylphosphonium bromide (cas: 28322-40-9) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Quality Control of Isopentyltriphenylphosphonium bromide
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary