Per-halogenation of primary hydroxy groups of 閻?cyclodextrin was written by Aoki, Nobuyoshi;Hattori, Kenjiro. And the article was included in Kenkyu Hokoku – Kanagawa-ken Sangyo Gijutsu Sogo Kenkyusho in 2005.HPLC of Formula: 53784-83-1 This article mentions the following:
Per-halogenation of primary hydroxyl groups of 閻?cyclodextrin (閻?CD) was investigated as an important way for the regioselective modification of 閻?CD. The high regioselectivity in the halogenation was discussed in terms of the reactivity to the SN2 reaction at each position on the anhydroglucopyranose unit. The reaction using halogenating reagent, such as, methanesulfonyl chloride, thionyl chloride, and thionyl bromide, yielded the corresponding per-6-chloro-per-6-deoxy-閻?CD (80 and 90% yield) or per-6-bromo-per-6-deoxy-閻?CD (70% yield) after several hours. The obtained product was halogenated only at C-6 and the halogenation at a secondary position was not observed The reactivity at C-3 of 閻?CD was lower than the corresponding reaction of other saccharides, such as cellulose. In the experiment, the researchers used many compounds, for example, Heptakis(6-Bromo-6-Deoxy)-閻?Cyclodextrin (cas: 53784-83-1HPLC of Formula: 53784-83-1).
Heptakis(6-Bromo-6-Deoxy)-閻?Cyclodextrin (cas: 53784-83-1) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. When the molecular ion is detected, the bromine and chlorine isotope patterns are very distinct, but caution is to be exercised for certain mixed chlorinated/brominated compounds, which can look similar to homohalogen patterns.HPLC of Formula: 53784-83-1
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary