1-Ethoxy-3-trifluoromethyl-1,3-butadiene and congeners as Diels-Alder components opening an entry to functionalized (trifluoromethyl)benzenes and -pyridines was written by Volle, Jean-Noel;Schlosser, Manfred. And the article was included in European Journal of Organic Chemistry in 2002.Related Products of 107317-58-8 This article mentions the following:
1-Ethoxy-3-trifluoromethyl-1,3-butadiene and its 2-bromo- and 2-phenyl-substituted derivatives have been prepared by Wittig methylenation of the corresponding 4-ethoxy-1,1,1-trifluoro-3-buten-2-ones, which in turn are readily accessible from trifluoroacetic acid. The electron-rich/electron-poor dienes combine smoothly with di-Me acetylenedicarboxylate and Me propiolate to provide trifluoromethyl-substituted phthalates or benzoates. Satisfactory yields of 4-(trifluoromethyl)pyridinecarboxylic acids can even be achieved with Me cyanoformate, a less reactive dienophile, if a large excess of the dienophile is employed. In the experiment, the researchers used many compounds, for example, Methyl 4-bromo-3-(trifluoromethyl)benzoate (cas: 107317-58-8Related Products of 107317-58-8).
Methyl 4-bromo-3-(trifluoromethyl)benzoate (cas: 107317-58-8) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Related Products of 107317-58-8
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary