Synthesis and antimalarial activity of chain substituted pivaloyloxymethyl ester analogues of Fosmidomycin and FR900098 was written by Kurz, Thomas;Schlueter, Katrin;Kaula, Uwe;Bergmann, Baerbel;Walter, Rolf D.;Geffken, Detlef. And the article was included in Bioorganic & Medicinal Chemistry in 2006.Safety of 2-(Bromomethyl)-1,3-dimethylbenzene This article mentions the following:
Fosmidomycin is a promising antimalarial drug candidate with a unique chem. structure and a novel mode of action. Chain substituted pivaloyloxymethyl ester derivatives of Fosmidomycin and its acetyl analog FR900098 have been synthesized and their in vitro antimalarial activity vs. the Chloroquine sensitive strain 3D7 of Plasmodium falciparum has been determined In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-1,3-dimethylbenzene (cas: 83902-02-7Safety of 2-(Bromomethyl)-1,3-dimethylbenzene).
2-(Bromomethyl)-1,3-dimethylbenzene (cas: 83902-02-7) belongs to organobromine compounds. Organo bromine compounds are versatile compounds and are widely used in diverse fields. Organo bromine derivatives are used in the dye sector, as an indicator in analytical chemistry (Bromothymol blue is a popular indicator). One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.Safety of 2-(Bromomethyl)-1,3-dimethylbenzene
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary