Photochromic dihetarylethenes. 12. Synthesis of 5-alkyl-2-(1,3,4-oxadiazol-2-yl)thiophenes and their photochromic derivatives was written by Krayushkin, M. M.;Stoyanovich, F. M.;Zolotarskaya, O. Yu.;Chernoburova, E. I.;Makhova, N. N.;Yarovenko, V. N.;Zavarzin, I. V.;Martynkin, A. Yu.;Uzhinov, B. M.. And the article was included in Chemistry of Heterocyclic Compounds (New York, NY, United States)(Translation of Khimiya Geterotsiklicheskikh Soedinenii) in 2002.Application In Synthesis of 4-Bromo-5-methylthiophene-2-carboxylic acid This article mentions the following:
Photochromic 5-alkyl-2-(1,3,4-oxadiazol-2-yl)thiophenes I (R1 = Me, R2 = Ph, 4-MeOC6H4; R1 = n-hexyl, R2 = 6-methoxy-2-benzothiazolyl) and II were synthesized, and their photochromic and fluorescent properties were studied. In the experiment, the researchers used many compounds, for example, 4-Bromo-5-methylthiophene-2-carboxylic acid (cas: 29421-99-6Application In Synthesis of 4-Bromo-5-methylthiophene-2-carboxylic acid).
4-Bromo-5-methylthiophene-2-carboxylic acid (cas: 29421-99-6) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Application In Synthesis of 4-Bromo-5-methylthiophene-2-carboxylic acid
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary