Synthesis and in-vitro evaluation of platelet aggregation inhibitory activity of paeonol and its analogs was written by Akamanchi, K. G.;Padmawar, P. A.;Thatte, U. M.;Rege, N. N.;Dahanukar, S. A.. And the article was included in Pharmacy and Pharmacology Communications in 1999.Safety of 3-Bromophenyl acetate This article mentions the following:
Paeonol (1-(2-hydroxy-4-methoxyphenyl)ethanone) and a series of substituted 1-(2-hydroxyphenyl)ethanone derivatives were synthesized and screened as inhibitors of platelet aggregation. The compounds with the greatest anti-platelet potential among the series tested were 1-(2,5-dihydroxyphenyl)ethanone (65.36% inhibition at 300 μM against 5 μM ADP), paeonol (36.31%), 1-(2-hydroxy-5-methoxyphenyl)ethanone (24.47%), 1-(2-hydroxy-5-nitrophenyl) ethanone (30.40%), and 1-(5-chloro-2-hydroxy-4-methylphenyl)ethanone (24.43%). In the experiment, the researchers used many compounds, for example, 3-Bromophenyl acetate (cas: 35065-86-2Safety of 3-Bromophenyl acetate).
3-Bromophenyl acetate (cas: 35065-86-2) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.Safety of 3-Bromophenyl acetate
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary