Copper-Catalyzed Carboarylation of Alkynes via Vinyl Cations was written by Walkinshaw, Andrew J.;Xu, Wenshu;Suero, Marcos G.;Gaunt, Matthew J.. And the article was included in Journal of the American Chemical Society in 2013.Quality Control of 1-(2-Bromoethyl)-4-methoxybenzene This article mentions the following:
Copper-catalyzed arylation of electron rich alkynes reveals stabilized trisubstituted vinyl cation equivalent that react with pendant arene nucleophiles to form all carbon tetrasubstituted alkenes, e.g. I. The new process streamlines the synthesis of important medicinally relevant mols. In the experiment, the researchers used many compounds, for example, 1-(2-Bromoethyl)-4-methoxybenzene (cas: 14425-64-0Quality Control of 1-(2-Bromoethyl)-4-methoxybenzene).
1-(2-Bromoethyl)-4-methoxybenzene (cas: 14425-64-0) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Quality Control of 1-(2-Bromoethyl)-4-methoxybenzene
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary