Catalytic, Directed C-C Bond Functionalization of Styrenes was written by Onodera, Shunsuke;Togashi, Ryo;Ishikawa, Soya;Kochi, Takuya;Kakiuchi, Fumitoshi. And the article was included in Journal of the American Chemical Society in 2020.Name: 3-Bromo-4-fluorotoluene This article mentions the following:
A method for catalytic conversion of C(aryl)-C(alkenyl) bonds in styrene derivatives R1-2-R2C6H3C(=CHR4)R3 (R1 = H, 4-Me, 3-Cl, 5-Me, etc.; R2 = 1-pyrazolyl, 2-pyridyl; R3 = H, Me, Ph, 4-methoxyphenyl, etc.; R4 = H, Ph, 4-chlorophenyl) to new C-C bonds is developed. In the presence of a rhodium catalyst, the alkenyl groups of styrenes bearing a pyrazolyl directing group were efficiently converted to other carbon substituents upon reacting with various alkenes RCH=CH2 (R = 4-methylhex-1-en-1-yl, 2-cyclohexylethenyl, 2-phenylethenyl, etc.) and allyl alcs. R5CH(OH)CH=CH2(R5 = cyclohexyl, Me, Et, etc.). It is also indicated that the C-C bond cleavage proceeded via a hydrometalation/β-carbon elimination pathway. In the experiment, the researchers used many compounds, for example, 3-Bromo-4-fluorotoluene (cas: 452-62-0Name: 3-Bromo-4-fluorotoluene).
3-Bromo-4-fluorotoluene (cas: 452-62-0) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.Name: 3-Bromo-4-fluorotoluene
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary