Design, synthesis and structure of new potential electrochemically active boronic acid-based glucose sensors was written by Norrild, Jens Chr.;Sotofte, Inger. And the article was included in Journal of the Chemical Society, Perkin Transactions 2 in 2002.HPLC of Formula: 166821-88-1 This article mentions the following:
In the authors’ studies on new boronic acid based carbohydrate sensors three new boronic acids (2-FcCH2NMeCH2C6H4B(OH)2 (3), 1,2-(2-(HO)2BC6H4CH2NMeCH2)2ferrocene (7) and 1,1′-(2-(HO)2BC6H4CH2NMeCH2)2ferrocene (11)) containing a ferrocene moiety were synthesized. Their design includes an intramol. B-N bonding motif to facilitate binding at physiol. pH. The authors report the synthesis of the compounds and studies on glucose complexation as studied by 13C NMR spectroscopy. The crystal structure of 2,4,6-tris[2-(N-ferrocenylmethyl-N-methylaminomethyl)phenyl]boroxin (13) (boroxin of boronic acid 3) (boroxin = cyclotriboroxane) was obtained and compared with structures obtained of 2,4,6-tris[2-(N,N-dimethylaminomethyl)phenyl]boroxin (14) and 2-(2-(dimethylaminomethyl)phenyl)-5,5-dimethyl-1,3,2-dioxaborinane (15). The structure of 13 shows the existence of intramol. B-N bonds in the solid phase. In the experiment, the researchers used many compounds, for example, 2-(2-(Bromomethyl)phenyl)-5,5-dimethyl-1,3,2-dioxaborinane (cas: 166821-88-1HPLC of Formula: 166821-88-1).
2-(2-(Bromomethyl)phenyl)-5,5-dimethyl-1,3,2-dioxaborinane (cas: 166821-88-1) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.HPLC of Formula: 166821-88-1
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary