Heteroaromatic boron compounds. XX. On the preparation of the 6,7-borazarobenzo[b]thiophene system. The preparation of some 3-(2-nitro-3-thienyl)acrylic esters and related compounds. A selective hydrogenation of a vinyl group in the presence of an aromatic nitro group was written by Gronowitz, S.;Ander, I.. And the article was included in Chemica Scripta in 1980.Recommanded Product: 18791-79-2 This article mentions the following:
Some Me 3-(2-nitro-3-thienyl)acrylic esters were prepared by nitration of the corresponding 3-(3-thienyl)acrylic esters. Nitration of 3-(3-thienyl)acrylic acid and its Me ester gave a mixture of 2- and 5-nitrated products. Reduction of the nitro groups to the corresponding 3-(2-amino-3-thienyl)acrylic esters failed. The reaction between 3-thiophenecarboxaldehyde and 5-bromo-3-thiophenecarboxaldehyde with cyanoacetic acid was investigated as to isomer distribution. Hydrogenation of 2-nitro-3-vinylthiophene with Pd/C gave 3-ethyl-2-nitrothiophene (42%) as the only detected product. 3-Nitro-2-vinylthiophene was hydrogenated to 2-ethyl-3-nitrothiophene and 3-amino-2-ethylthiophene. 2-Nitro-3-[2-(2-thienyl)ethenyl]thiophene, was converted on hydrogenation to the unstable 2-amino-3-[2-(2-thienyl)ethenyl]thiophene, which with PhBCl2 gave 6-phenyl-5-(2-thienyl)-6,7-borazarobenzo[b]thiophene (I). Desulfurization of this compound gave 2,1-borazarene (II) and lower homologs. In the experiment, the researchers used many compounds, for example, 5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2Recommanded Product: 18791-79-2).
5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Recommanded Product: 18791-79-2
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary