Total Synthesis of Glycinocins A-C was written by Corcilius, Leo;Elias, Nabiha T.;Ochoa, Jessica L.;Linington, Roger G.;Payne, Richard J.. And the article was included in Journal of Organic Chemistry in 2017.Application of 28322-40-9 This article mentions the following:
The glycinocins are a class of calcium-dependent, acidic cyclolipopeptide antibiotics structurally related to the clin. approved daptomycin. Herein, we describe a divergent total synthesis of glycinocins A-C, which differ in the structure of a branched α,β-unsaturated fatty acyl moiety. The three natural products exhibited calcium-dependent antimicrobial activity against Staphylococcus aureus and Bacillus subtilis with MICs ranging from 5.5 to 17 μM. In the experiment, the researchers used many compounds, for example, Isopentyltriphenylphosphonium bromide (cas: 28322-40-9Application of 28322-40-9).
Isopentyltriphenylphosphonium bromide (cas: 28322-40-9) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Application of 28322-40-9
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary