Visible-Light-Enabled Decarboxylative Mono- and Difluoromethylation of Cinnamic Acids under Metal-Free Conditions was written by Tang, Wei-Ke;Feng, Yi-Si;Xu, Zhuo-Wei;Cheng, Zhi-Fei;Xu, Jun;Dai, Jian-Jun;Xu, Hua-Jian. And the article was included in Organic Letters in 2017.Electric Literature of C9H6BrFO2 This article mentions the following:
Several new mono- and difluoromethylation reactions of cinnamic acids using an Eosin Y catalytic system are reported. An efficient alkene fluoromethylation of α,β-unsaturated carboxylic acids, e.g., I, II, and III, was accomplished under ambient temperature and metal-free conditions, with a wide range of functional group tolerance. A mechanism that involves a radical process is proposed for this reaction. In the experiment, the researchers used many compounds, for example, 3-Bromo-4-fluorocinnamic acid (cas: 160434-49-1Electric Literature of C9H6BrFO2).
3-Bromo-4-fluorocinnamic acid (cas: 160434-49-1) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Electric Literature of C9H6BrFO2
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary