Antitubercular agents. Part 1: Synthesis of phthalimido- and naphthalimido-linked phenazines as new prototype antitubercular agents was written by Kamal, Ahmed;Hari Babu, A.;Venkata Ramana, A.;Sinha, Rakesh;Yadav, J. S.;Arora, Sudarshan K.. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2005.Name: N-(5-Bromopentyl)phthalimide This article mentions the following:
The preparation and antitubercular properties of a series of phthalimido- and naphthalimido-linked phenazines, e.g., I, are described. Some of these compounds inhibited the growth of Mycobacterium tuberculosis ATCC 27294, Mycobacterium avium ATCC 49601, Mycobacterium intracellulare ATCC 13950, and some clin. isolates. In the experiment, the researchers used many compounds, for example, N-(5-Bromopentyl)phthalimide (cas: 954-81-4Name: N-(5-Bromopentyl)phthalimide).
N-(5-Bromopentyl)phthalimide (cas: 954-81-4) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.Name: N-(5-Bromopentyl)phthalimide
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary