Ito, Shigekazu et al. published their research in ChemistrySelect in 2016 | CAS: 162258-89-1

4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Safety of 4-Bromo-4′-tert-butylbiphenyl

Palladium-Catalyzed Arylation of a Sterically Demanding gem-Dibromophosphaethene was written by Ito, Shigekazu;Shinozaki, Tomokazu;Mikami, Koichi. And the article was included in ChemistrySelect in 2016.Safety of 4-Bromo-4′-tert-butylbiphenyl This article mentions the following:

The trans bromide of 2,2-dibromo-1-(2,4,6-tri-t-butylphenyl)-1-phosphaethene (Mes*P:CBr2; Mes* = 2,4,6-tBu3C6H2) can be successfully substituted with an aryl group by using a palladium version of the Kumada-Tamao-Corriu cross-coupling process. Predominant formation of the 2-aryl-2-bromo-1-phosphaethene [(Z)-Mes*P:C(Br)Ar] required suitable conditions including optimization of the ancillary phosphine ligand, thereby retarding the dual elimination of bromides leading to phosphaalkyne (Mes*CP). The 2-aryl-2-bromo-1-phosphaethenes hold promise as versatile synthons for functional π-conjugated mols., and stereospecific transformations of the bromine atom by halogen-metal exchange and palladium-catalyzed arylations were demonstrated. In the experiment, the researchers used many compounds, for example, 4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1Safety of 4-Bromo-4′-tert-butylbiphenyl).

4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Safety of 4-Bromo-4′-tert-butylbiphenyl

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary