Study of interactions between alcohol and amine functions. Thermolysis of hydroxides and salts of ω-(trialkylammonio)-1-alkanols was written by Barbry, Didier;Hasiak, Bruno. And the article was included in Collection of Czechoslovak Chemical Communications in 1983.Reference of 50592-87-5 This article mentions the following:
Products of the thermolysis of R3N+(CH2)nOH.OH– (I; R = Me, Et, Pr; n = 4-8) were identified. Major products were HO(CH2)n-2CH:CH2 and HO(CH2)nR2. Intramol. cyclization was only important for I (R = Me, n = 4; R = Pr, n = 5) giving 91.5% THF and 21.7% tetrahydropyran, resp. RO(CH2)n-2CH:CH2 and RO(CH2)nNR2 (R = Me, n = 6,7) were formed in 17.6-20.6% yields. Thermal decomposition of Me3N+(CH2)nOH.OAc– (n = 5, 6) gave 90.6% and 82.4% HO(CH2)nNMe2 (n = 5, 6) and 5.6% and 16.0% AcO(CH2)nNMe2 (n = 5, 6), resp. Pyrolysis of HO(CH2)6N+Me3.Cl– gave 82.4% HO(CH2)6NMe2 and 8.2% HO(CH2)6Cl. In the experiment, the researchers used many compounds, for example, 1-Bromo-6-methoxyhexane (cas: 50592-87-5Reference of 50592-87-5).
1-Bromo-6-methoxyhexane (cas: 50592-87-5) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Reference of 50592-87-5
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary