Ruthenium-catalyzed selective synthesis of monoalkylated barbituric acids through “borrowing hydrogen” methodology was written by Putra, Anggi Eka;Oe, Yohei;Ohta, Tetsuo. And the article was included in Tetrahedron Letters in 2017.COA of Formula: C7H7BrO2 This article mentions the following:
An environmentally benign alkylation of barbituric acids via “borrowing hydrogen” process with ruthenium catalysis was established. The corresponding 5-(alkyl)barubituric acids were obtained in good to excellent yields with low catalyst loading. Various substrates including aliphatic alcs. were tolerated in the present catalytic system. A novel method for construction of barbituric acid-fused benzopyrane derivatives was also demonstrated. In the experiment, the researchers used many compounds, for example, 5-Bromo-2-(hydroxymethyl)phenol (cas: 170434-11-4COA of Formula: C7H7BrO2).
5-Bromo-2-(hydroxymethyl)phenol (cas: 170434-11-4) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.COA of Formula: C7H7BrO2
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary