Synthesis of esters by rhodium(I)-catalyzed borate ester-benzylic bromide carbonylation reactions was written by Woell, James B.;Alper, Howard. And the article was included in Tetrahedron Letters in 1984.Quality Control of Ethyl (2-bromophenyl)acetate This article mentions the following:
RCH2CO2R1 (R = Ph, m– or p-tolyl, o-BrC6H4, 2-naphthyl; R1 = C2-C4 alkyl) were obtained in 46-100% yields by bubbling CO through a mixture of RCH2Br, B(OR1)3, and 1,5-hexadienerhodium chloride dimer at 75°/1 atm. In the experiment, the researchers used many compounds, for example, Ethyl (2-bromophenyl)acetate (cas: 2178-24-7Quality Control of Ethyl (2-bromophenyl)acetate).
Ethyl (2-bromophenyl)acetate (cas: 2178-24-7) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Quality Control of Ethyl (2-bromophenyl)acetate
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary