Aromatic sulfonyl fluorides. III was written by Steinkopf, Wilhelm;Hubner, Rolf. And the article was included in Journal fuer Praktische Chemie (Leipzig) in 1934.COA of Formula: C6H4BrFO2S This article mentions the following:
An 86% yield of p-EtC6H4SO2F (I), b. 238-9°, b14 124.5°, is obtained from 50 g. EtPh and 200 g. FSO3H, together with a small amount of (p-EtC6H4)2SO2, m. 98°, but no trace of a disulfonyl fluoride. The nitration of I gives 4,3-Et(O2N)C6H3SO2F, b15 179°. Adding 25 g. MeI and 5 g. Mg in 200 cc. of ether to 16 g. of I in 100 cc. of ether gives 7.3 g. of (p-EtC6H4SO2)2CH2, m. 131°, soluble in alc., ether and hot KOH, not soluble in H2O. Adding 16 g. BrPh and 2.8 g. Mg in 150 cc. ether to 10 g. of I in 150 cc. ether gives 4.2 g. of p-EtC6H4SO2Ph, m. 91.5-2.0°. Adding 25 g. MeI and 5 g. Mg in 100 cc. of ether to 10.5 g. of 2,4-Me2C6H3SO2F (II) gives 7.75 g. of (2,4-Me2-C6H3SO2)2CH2, m. 155.5-6.0°. Adding 20 g. BrPh and 6 g. Mg in 300 cc. ether to 13 g. of II gives 5.7 g. of 2,4-Me2C6H3SO2Ph, m. 87°. Adding 15 g. of 1,3-dimethyl-2,4-benzenedisulfonyl fluoride (III) to 25 g. MeI and 5.4 g. Mg in 150 cc. ether gives a mixture of C17H18O6F2S4, m. 135°, C17H18O6F2S4, m. 272°, and 1,3,2,4-Me2 (MeO2S)2-C6H2, m. 187°. Adding 16 g. BrPh and 2.6 g. Mg in 100 cc, ether to 12 g. of III in 250 cc. ether gives 7 g. of 1,3,2,4-Me2(PhO2S)2C6H2, m. 232-3°. Adding 14.3 g. of 1,5-dichloropentane and 5 g. Mg in ether slowly to 42 g. of II in ether gives 11 g. of 2,4-Me2C6H3SO2(CH2)5-O2SC6H3Me2-2,4, m. 98°. A Sandmeyer reaction gives (from the amino derivative) 60% of m-ClC6H4SO2F, b22 90°, or m-BrC6H4SO2F, b23 122°, the nitration of which gives 3,4-Cl(O2N)C6H3SO2F, m. 85° (81% yield), or 3,4-Br-(O2N)C6H3SO2F, m. 104° (84% yield), resp. The compounds described are new. In the experiment, the researchers used many compounds, for example, 3-Bromobenzene-1-sulfonyl fluoride (cas: 454-65-9COA of Formula: C6H4BrFO2S).
3-Bromobenzene-1-sulfonyl fluoride (cas: 454-65-9) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.COA of Formula: C6H4BrFO2S
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary