tBuOK-Promoted Cyclization of Imines with Aryl Halides was written by Li, Ya-Wei;Zheng, Hong-Xing;Yang, Bo;Shan, Xiang-Huan;Qu, Jian-Ping;Kang, Yan-Biao. And the article was included in Organic Letters in 2020.COA of Formula: C7H5Br2F This article mentions the following:
A transition-metal-free indole synthesis using radical coupling of 2-halotoluenes and imines via the later-stage C-N bond construction was reported for the first time. It includes an aminyl radical generation by C-H cleaving addition of 2-halotoluenes to imines via the carbanion radical relay and an intramol. coupling of aryl halides with aminyl radicals. One standard condition can be used for all halides including F, Cl, Br, and I. No extra oxidant or transition metal is required. In the experiment, the researchers used many compounds, for example, 2-Bromo-4-fluorobenzylbromide (cas: 61150-57-0COA of Formula: C7H5Br2F).
2-Bromo-4-fluorobenzylbromide (cas: 61150-57-0) belongs to organobromine compounds. Organo bromine compounds are versatile compounds and are widely used in diverse fields. Organo bromine derivatives are used in the dye sector, as an indicator in analytical chemistry (Bromothymol blue is a popular indicator). Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.COA of Formula: C7H5Br2F
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary