Preparation of oxacylanes. III. Mechanism of the cyclization of γ and δ halogenated methyl ethers in the presence of Lewis acids; isolation of intermediary oxonium salts was written by Kirrmann, Albert;Wartski, Lya. And the article was included in Bulletin de la Societe Chimique de France in 1966.Recommanded Product: 4457-67-4 This article mentions the following:
That the title cyclization takes place via the tertiary oxonium salts is confirmed (loc. cit.) by the isolation of the following intermediate salts: methyl tetrahydrofuranyl oxonium bromopentachloroantimonate (I), m. 110°, and methyl tetrahydropyranyl oxonium fluoborate (II). On heating, I gave tetrahydrofuran, MeBr and traces of MeCl while II gave tetrahydropyranate-BF3, b. 171°. In the experiment, the researchers used many compounds, for example, 1-Bromo-4-methoxybutane (cas: 4457-67-4Recommanded Product: 4457-67-4).
1-Bromo-4-methoxybutane (cas: 4457-67-4) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbonbromine bond is electrophilic in nature. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Recommanded Product: 4457-67-4
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary