A convergent total synthesis of a new antiepileptic ceramide and its triacetyl derivative using olefin cross metathesis was written by Ghosal, Partha;Kumar, Vikas;Shaw, Arun K.. And the article was included in Tetrahedron in 2010.Safety of Isopentyltriphenylphosphonium bromide This article mentions the following:
A convergent total synthesis of a new antiepileptic ceramide I and its triacetyl derivative was completed by using two important C-C bond forming reactions, Wittig methylenation and olefin cross metathesis as the key steps. The easily available 3,4,6-tri-O-benzyl-
Isopentyltriphenylphosphonium bromide (cas: 28322-40-9) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.Safety of Isopentyltriphenylphosphonium bromide
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary