Wang, Yan’en published the artcileTriazole-linked fluorescent bisboronic acid capable of selective recognition of the Lewis Y antigen, Formula: C12H16BBrO2, the publication is Bioorganic & Medicinal Chemistry Letters (2017), 27(9), 1983-1988, database is CAplus and MEDLINE.
Cell surface carbohydrates of the Lewis blood group antigens, Lewis X (Lex), Lewis Y (Ley), Lewis A (Lea), and their sialylated derivatives, such as sialy Lewis X (sLex) and sialy Lewis A (sLea), play important roles in various recognition processes. These cell surface carbohydrates have also been associated with the development and progression of many types of cancers. Recently, we synthesized four anthracene-based fluorescent bisboronic acid sensors (compounds 2a-d) linked by ‘click’ chem. with tethers of different lengths to match the epitope of various Lewis group of sugars. Among the four compounds, 2a appears to have both high sensitivity and selectivity for Ley among other carbohydrate antigens.
Bioorganic & Medicinal Chemistry Letters published new progress about 166821-88-1. 166821-88-1 belongs to bromides-buliding-blocks, auxiliary class Bromide,Boronic acid and ester,Benzyl bromide,Benzene,Boronic Acids,Boronic acid and ester, name is 2-(2-(Bromomethyl)phenyl)-5,5-dimethyl-1,3,2-dioxaborinane, and the molecular formula is C15H21BO2, Formula: C12H16BBrO2.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary